Archive for November, 2009
Stem Cell Research & Save $250 on Cord Blood Banking–See More Info link for details!
Last Updated on Monday, 30 November 2009 01:08 Written by admin Monday, 30 November 2009 01:08
DISCLAIMER: Please consult with your primary care physician before starting this or any other natural supplement. To learn more about cord blood banking see: www.cordblood.com To register, ask for Erin and tell her that Dr. Ahuva Gamliel referred you! Use the mom code: M1975 to save 0 when you enroll on-line or save 0 when you enroll by phone! To learn more about enhancing your health & wellbeing by boosting your own stem cells watch the 9 minute video on optimalhealth613.stemtechbiz …
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I am a single mom to be, and I want to do cord blood banking. Doctors say it’s a scam. Opinions??
Last Updated on Saturday, 28 November 2009 05:31 Written by admin Saturday, 28 November 2009 05:31
Even if the baby (my 1st child) has a slim chance of using the stem cells, I feel it’s like an insurance policy of sorts. I would pay far more financially and emotionally (and the child would pay more physically) if I didn’t pay this K for cord blood banking and the child could have used them in the near, or distant, future. Plus, I am more excited about future breakthroughs in stem cell research as the diseases they aim to treat are more common and run in my family (e.g., diabetes, heart disease, parkinsons and alzheimers). Would anyone with real experience or a personal story that’s related to this topic, or with advice, please answer? Thank you kindly…I deliver in about a month, so time is of the essence.
Technorati Tags: Aim, Alzheimers, Cord Blood Banking, Diabetes, Diseases, Distant Future, Doctors, Heart Disease, Insurance, Insurance Policy, Parkinsons, Personal Story, Single Mom, Slim Chance, Sorts, Stem Cell Research, Stem Cells, Time Is Of The Essence
Tags: Aim, Alzheimers, Cord Blood Banking, Diabetes, Diseases, Distant Future, Doctors, Heart Disease, Insurance, Insurance Policy, Parkinsons, Personal Story, Single Mom, Slim Chance, Sorts, Stem Cell Research, Stem Cells, Time Is Of The Essence | Posted under Cord Blood Banking | Comments
Stem Cells Heal Lungs Of Newborn Animals – Proven By Physician-Scientist
Last Updated on Saturday, 28 November 2009 12:00 Written by Saturday, 28 November 2009 12:00
Dr. Bernard Thbaud lives in two very different worlds. As a specialist in the Stollery Children’s Hospital’s Neonatal Intensive Care Unit at the Royal Alexandra Hospital, he cares for tiny babies, many of whom struggle for breath after being born weeks before they are due. Across town, in his laboratory in the Faculty of Medicine & Dentistry at the University of Alberta, Dr. Thbaud dons a lab coat and peers into a microscope to examine the precise effect of stem cells on the lungs.
With his scientific research being published in the American Journal of Respiratory and Critical Care Medicine, Dr. Thbaud has made a significant leap to bridge the gap between those two worlds.
An international team of scientists led by Dr. Thbaud has demonstrated for the first time that stem cells protect and repair the lungs of newborn rats. “The really exciting thing that we discovered was that stem cells are like little factories, pumping out healing factors,” says Dr. Thbaud, an Alberta Heritage Foundation for Medical Research Clinical Scholar. “That healing liquid seems to boost the power of the healthy lung cells and helps them to repair the lungs.”
In this study, Thbaud’s team simulated the conditions of prematurity – giving the newborn rats oxygen. The scientists then took stem cells, derived from bone marrow, and injected them into the rats’ airways. Two weeks later, the rats treated with stem cells were able to run twice as far, and had better survival rates. When Thbaud’s team looked at the lungs, they found the stem cells had repaired the lungs, and prevented further damage.
“I want to congratulate Dr. Thbaud and his team. This research offers real hope for a new treatment for babies with chronic lung disease,” says Dr. Roberta Ballard, professor of pediatrics, University of California, San Francisco. “In a few short years, I anticipate we will be able to take these findings and begin clinical trials with premature babies.”
“The dilemma we face with these tiny babies is a serious one. When they are born too early, they simply cannot breathe on their own. To save the babies’ lives, we put them on a ventilator and give them oxygen, leaving many of them with chronic lung disease,” says Dr. Thbaud. “Before the next decade is out I want to put a stop to this devastating disease.”
The research team includes physicians and scientists from Edmonton, Alberta, Tours, France, Chicago, Illinois, and Montreal, Quebec.
The team is now investigating the long-term safety of using stem cells as a lung therapy. The scientists are examining rats at 3 months, and 6 months after treatment, studying the lungs, and checking their organs to rule out any risk of cancer. Dr. Thbaud’s team is also exploring whether human cord blood is a better option than bone marrow stem cells in treating lung disease.
“We are also studying closely the healing liquid produced by the stem cells,” says Dr. Thbaud. “If that liquid can be used on its own to grow and repair the lungs, that might make the injection of stem cells unnecessary.”
Dr. Thbaud is a neonatal specialist for Alberta Health Services, and a Canada Research Chair in Translational Lung and Vascular Development Biology. His research is supported by the AHFMR, the Canada Foundation for Innovation, the Canadian Institutes of Health Research, the Canadian Stem Cell Network and the Stollery Children’s Hospital Foundation.
The study, Airway Delivery of Mesenchymal Stem Cells prevents Arrested Alveolar Growth In Neonatal Lung Injury In Rats, is available at http://ajrccm.atsjournals.org/current.shtml
Background:
Alberta has the highest rate of premature births in Canada with a rate of 9.2% compared to the rest of Canada at 7.8%.
Babies who are born extremely premature – before 28 weeks – cannot breathe on their own. In order to help the babies’ lungs to develop, neonatal doctors give them oxygen and drugs to help them breathe.
These treatments contribute to a chronic lung disease known as Bronchopulmonary dysplasia (BPD). At present there is no treatment to heal the lungs of these premature babies.
50% of babies born before 28 weeks will get chronic lung disease. Case studies have shown that as these babies grow up, they continue to struggle with lung disease, coping with reduced lung function and early aging of their lungs.
Source: Karen Thomas
Alberta Heritage Foundation for Medical Research
Stem Cells Heal Lungs Of Newborn Animals – Proven By Physician-Scientist
Originally from:
http://www.medicalnewstoday.com/articles/172353.php
Technorati Tags: alberta, Babies, california, chicago, faculty, health, medical, source, Stem Cells, stollery, university
Tags: alberta, Babies, california, chicago, faculty, health, medical, source, Stem Cells, stollery, university | Posted under Cord Blood, Stem Cells | Comments
The Birth Of New Neurons Boosted By Polyphenols And Polyunsaturated Fatty Acids
Last Updated on Thursday, 26 November 2009 12:00 Written by Thursday, 26 November 2009 12:00
Universitat Autnoma de Barcelona (UAB) researchers have confirmed that a diet rich in polyphenols and polyunsaturated fatty acids, patented as an LMN diet, helps boost the production of the brain’s stem cells -neurogenesis- and strengthens their differentiation in different types of neuron cells. The research revealed that mice fed an LMN diet, when compared to those fed a control diet, have more cell proliferation in the two areas of the brain where neurogenesis is produced, the olfactory bulb and the hippocampus, both of which are greatly damaged in patients with Alzheimer’s disease. These results give support to the hypothesis that a diet made up of foods rich in these antioxidant substances could delay the onset of this disease or even slow down its evolution.
The study will be published in the December issue of the Journal of Alzheimer’s Disease and was directed by Mercedes Unzeta, professor of the UAB Department of Biochemistry and Molecular Biology. Participating in the study were researchers from this department and from the departments of Cell Biology, Physiology and Immunology, and of Psychiatry and Legal Medicine, all of which are affiliated centres of the Institute of Neuroscience of Universitat Autnoma de Barcelona. The company La Morella Nuts from Reus and the ACE Foundation of the Catalan Institute of Applied Neurosciences also collaborated in the study.
Polyphenols can be found in tea, beer, grapes, wine, olive oil, cocoa, nuts and other fruits and vegetables. Polyunsaturated fatty acids can be found in blue fish and vegetables such as corn, soya beans, sunflowers and pumpkins. The LMN cream used in this study was composed of a mixture of natural products: dried fruits and nuts, coconut, vegetable oils rich in polyunsaturated fat and flour rich in soluble fiber. These creams were created and patented by the company La Morella Nuts, located in Reus near Tarragona. Previous studies had verified their effects on regulating cholesterol levels and hypertension, two risk factors commonly associated with heart disease and Alzheimer’s disease.
During the development of the brain, stem cells generate different neural cells (neurons, astrocytes and oligodendrocytes) which end up forming the adult brain. Until the 1960s it was thought that the amount of neurons in adult mammals decreased with age and that the body was not able to renew these cells. Now it is known that new neurons are formed in the adult brain. This generative capacity of the cells however is limited to two areas of the brain: the olfactory bulb and the hippocampus (area related to the memory and to cognitive processes). Although the rhythm of cell proliferation decreases with age and with neurodegenerative diseases, it is known that exercise and personal well being can combat this process.
The main objective of this research was to study the effect of an LMN cream-enriched diet on the neurogenesis of the brain of an adult mouse. Scientists used two groups of mice for the study. One group was given a normal diet and the other was given the same diet enriched with LMN cream. Both groups were fed during 40 days (approximately five years in humans). The analyses carried out in different brain regions demonstrated that those fed with LMN cream had a significantly higher amount of stem cells, as well as new differentiated cells, in the olfactory bulb and hippocampus.
The second objective was to verify if the LMN cream could prevent damage caused by oxidation or neural death in cell cultures. Cultures of the hippocampal and cortical cells were pretreated with LMN cream. After causing oxidative damage with hydrogen peroxide, which killed 40% of the cells, scientists observed that a pretreatment with LMN cream was capable of diminishing, and in some cases completely preventing, oxidative damage. The hippocampal and cortical cells were also damaged using amyloid beta (anomalous deposits of this protein are related to Alzheimer’s disease). The results obtained were similar to those obtained using hydrogen peroxide.
These results demonstrate that an LMN diet is capable of inducing the generation of new cells in the adult brain, and of strengthening the neural networks which become affected with age and in neurogenerative processes such as Alzheimer’s disease, as well as protecting neurons from oxidative and neural damage, two phenomena which occur at the origin of many diseases affecting the central nervous system.
In this study researchers have used different biochemical and molecular analysis techniques, with the help of specific antibodies, to detect different neuronal markers implied in the process of differentiation.
The group of researchers led by Dr Unzeta has spent years studying the effects oxidases have on oxidative stress as a factor implied in neurodegenerative disorders such as Parkinson and Alzheimer’s disease, and the effects of different natural products with anti-inflammatory and antioxidant properties in different experimental models of Alzheimer’s disease.
The study forms part of the CENIT project, which was awarded to La Morella Nuts in 2006 under the auspices of the INGENIO 2010 programme, with the objective of establishing methodologies for the design, evaluation and verification of functional foods which may protect against cardiovascular diseases and Alzheimer’s disease. With 21.15m euros in funding and a duration of four years, the project has included the participation of 50 doctors and technicians from nine different companies, four universities (7 departments) and 2 research centres.
Reference article: “A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adults mouse brain”. Valente et al., 2009, Journal of Alzheimer’s Disease, Volume 18:4. Valente T., Hidalgo, J., Bolea, I., Ramrez B., Angls, N., Reguant, J., Morell, J.R., Gutirrez, C., Boada, M., Unzeta, M.
Source: Maria Jesus Delgado
Universitat Autonoma de Barcelona
The Birth Of New Neurons Boosted By Polyphenols And Polyunsaturated Fatty Acids
Originally from:
http://www.medicalnewstoday.com/articles/172157.php
Technorati Tags: alberta, Alzheimer, california, chicago, development, Differentiation, effects, faculty, health, journal, process, project, source, Stem Cells, university
Tags: alberta, Alzheimer, california, chicago, development, Differentiation, effects, faculty, health, journal, process, project, source, Stem Cells, university | Posted under Stem Cells | Comments