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Archive for November, 2009

Stem Cell Research & Save $250 on Cord Blood Banking–See More Info link for details!

November 30, 2009 By: admin Category: Cord Blood Videos Comments

DISCLAIMER: Please consult with your primary care physician before starting this or any other natural supplement. To learn more about cord blood banking see: www.cordblood.com To register, ask for Erin and tell her that Dr. Ahuva Gamliel referred you! Use the mom code: M1975 to save 0 when you enroll on-line or save 0 when you enroll by phone! To learn more about enhancing your health & wellbeing by boosting your own stem cells watch the 9 minute video on optimalhealth613.stemtechbiz …

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I am a single mom to be, and I want to do cord blood banking. Doctors say it’s a scam. Opinions??

November 28, 2009 By: admin Category: Cord Blood Banking Comments

Even if the baby (my 1st child) has a slim chance of using the stem cells, I feel it’s like an insurance policy of sorts. I would pay far more financially and emotionally (and the child would pay more physically) if I didn’t pay this K for cord blood banking and the child could have used them in the near, or distant, future. Plus, I am more excited about future breakthroughs in stem cell research as the diseases they aim to treat are more common and run in my family (e.g., diabetes, heart disease, parkinsons and alzheimers). Would anyone with real experience or a personal story that’s related to this topic, or with advice, please answer? Thank you kindly…I deliver in about a month, so time is of the essence.

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Stem Cells Heal Lungs Of Newborn Animals – Proven By Physician-Scientist

November 28, 2009 By: Category: Cord Blood, Stem Cells Comments

Dr. Bernard Thbaud lives in two very different worlds. As a specialist in the Stollery Children’s Hospital’s Neonatal Intensive Care Unit at the Royal Alexandra Hospital, he cares for tiny babies, many of whom struggle for breath after being born weeks before they are due. Across town, in his laboratory in the Faculty of Medicine & Dentistry at the University of Alberta, Dr. Thbaud dons a lab coat and peers into a microscope to examine the precise effect of stem cells on the lungs.

With his scientific research being published in the American Journal of Respiratory and Critical Care Medicine, Dr. Thbaud has made a significant leap to bridge the gap between those two worlds.

An international team of scientists led by Dr. Thbaud has demonstrated for the first time that stem cells protect and repair the lungs of newborn rats. “The really exciting thing that we discovered was that stem cells are like little factories, pumping out healing factors,” says Dr. Thbaud, an Alberta Heritage Foundation for Medical Research Clinical Scholar. “That healing liquid seems to boost the power of the healthy lung cells and helps them to repair the lungs.”

In this study, Thbaud’s team simulated the conditions of prematurity – giving the newborn rats oxygen. The scientists then took stem cells, derived from bone marrow, and injected them into the rats’ airways. Two weeks later, the rats treated with stem cells were able to run twice as far, and had better survival rates. When Thbaud’s team looked at the lungs, they found the stem cells had repaired the lungs, and prevented further damage.

“I want to congratulate Dr. Thbaud and his team. This research offers real hope for a new treatment for babies with chronic lung disease,” says Dr. Roberta Ballard, professor of pediatrics, University of California, San Francisco. “In a few short years, I anticipate we will be able to take these findings and begin clinical trials with premature babies.”

“The dilemma we face with these tiny babies is a serious one. When they are born too early, they simply cannot breathe on their own. To save the babies’ lives, we put them on a ventilator and give them oxygen, leaving many of them with chronic lung disease,” says Dr. Thbaud. “Before the next decade is out I want to put a stop to this devastating disease.”

The research team includes physicians and scientists from Edmonton, Alberta, Tours, France, Chicago, Illinois, and Montreal, Quebec.

The team is now investigating the long-term safety of using stem cells as a lung therapy. The scientists are examining rats at 3 months, and 6 months after treatment, studying the lungs, and checking their organs to rule out any risk of cancer. Dr. Thbaud’s team is also exploring whether human cord blood is a better option than bone marrow stem cells in treating lung disease.

“We are also studying closely the healing liquid produced by the stem cells,” says Dr. Thbaud. “If that liquid can be used on its own to grow and repair the lungs, that might make the injection of stem cells unnecessary.”

Dr. Thbaud is a neonatal specialist for Alberta Health Services, and a Canada Research Chair in Translational Lung and Vascular Development Biology. His research is supported by the AHFMR, the Canada Foundation for Innovation, the Canadian Institutes of Health Research, the Canadian Stem Cell Network and the Stollery Children’s Hospital Foundation.

The study, Airway Delivery of Mesenchymal Stem Cells prevents Arrested Alveolar Growth In Neonatal Lung Injury In Rats, is available at http://ajrccm.atsjournals.org/current.shtml

Background:


Alberta has the highest rate of premature births in Canada with a rate of 9.2% compared to the rest of Canada at 7.8%.


Babies who are born extremely premature – before 28 weeks – cannot breathe on their own. In order to help the babies’ lungs to develop, neonatal doctors give them oxygen and drugs to help them breathe.


These treatments contribute to a chronic lung disease known as Bronchopulmonary dysplasia (BPD). At present there is no treatment to heal the lungs of these premature babies.


50% of babies born before 28 weeks will get chronic lung disease. Case studies have shown that as these babies grow up, they continue to struggle with lung disease, coping with reduced lung function and early aging of their lungs.

Source: Karen Thomas

Alberta Heritage Foundation for Medical Research

Stem Cells Heal Lungs Of Newborn Animals – Proven By Physician-Scientist

Originally from:
http://www.medicalnewstoday.com/articles/172353.php

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The Birth Of New Neurons Boosted By Polyphenols And Polyunsaturated Fatty Acids

November 26, 2009 By: Category: Stem Cells Comments

Universitat Autnoma de Barcelona (UAB) researchers have confirmed that a diet rich in polyphenols and polyunsaturated fatty acids, patented as an LMN diet, helps boost the production of the brain’s stem cells -neurogenesis- and strengthens their differentiation in different types of neuron cells. The research revealed that mice fed an LMN diet, when compared to those fed a control diet, have more cell proliferation in the two areas of the brain where neurogenesis is produced, the olfactory bulb and the hippocampus, both of which are greatly damaged in patients with Alzheimer’s disease. These results give support to the hypothesis that a diet made up of foods rich in these antioxidant substances could delay the onset of this disease or even slow down its evolution.

The study will be published in the December issue of the Journal of Alzheimer’s Disease and was directed by Mercedes Unzeta, professor of the UAB Department of Biochemistry and Molecular Biology. Participating in the study were researchers from this department and from the departments of Cell Biology, Physiology and Immunology, and of Psychiatry and Legal Medicine, all of which are affiliated centres of the Institute of Neuroscience of Universitat Autnoma de Barcelona. The company La Morella Nuts from Reus and the ACE Foundation of the Catalan Institute of Applied Neurosciences also collaborated in the study.

Polyphenols can be found in tea, beer, grapes, wine, olive oil, cocoa, nuts and other fruits and vegetables. Polyunsaturated fatty acids can be found in blue fish and vegetables such as corn, soya beans, sunflowers and pumpkins. The LMN cream used in this study was composed of a mixture of natural products: dried fruits and nuts, coconut, vegetable oils rich in polyunsaturated fat and flour rich in soluble fiber. These creams were created and patented by the company La Morella Nuts, located in Reus near Tarragona. Previous studies had verified their effects on regulating cholesterol levels and hypertension, two risk factors commonly associated with heart disease and Alzheimer’s disease.

During the development of the brain, stem cells generate different neural cells (neurons, astrocytes and oligodendrocytes) which end up forming the adult brain. Until the 1960s it was thought that the amount of neurons in adult mammals decreased with age and that the body was not able to renew these cells. Now it is known that new neurons are formed in the adult brain. This generative capacity of the cells however is limited to two areas of the brain: the olfactory bulb and the hippocampus (area related to the memory and to cognitive processes). Although the rhythm of cell proliferation decreases with age and with neurodegenerative diseases, it is known that exercise and personal well being can combat this process.

The main objective of this research was to study the effect of an LMN cream-enriched diet on the neurogenesis of the brain of an adult mouse. Scientists used two groups of mice for the study. One group was given a normal diet and the other was given the same diet enriched with LMN cream. Both groups were fed during 40 days (approximately five years in humans). The analyses carried out in different brain regions demonstrated that those fed with LMN cream had a significantly higher amount of stem cells, as well as new differentiated cells, in the olfactory bulb and hippocampus.

The second objective was to verify if the LMN cream could prevent damage caused by oxidation or neural death in cell cultures. Cultures of the hippocampal and cortical cells were pretreated with LMN cream. After causing oxidative damage with hydrogen peroxide, which killed 40% of the cells, scientists observed that a pretreatment with LMN cream was capable of diminishing, and in some cases completely preventing, oxidative damage. The hippocampal and cortical cells were also damaged using amyloid beta (anomalous deposits of this protein are related to Alzheimer’s disease). The results obtained were similar to those obtained using hydrogen peroxide.

These results demonstrate that an LMN diet is capable of inducing the generation of new cells in the adult brain, and of strengthening the neural networks which become affected with age and in neurogenerative processes such as Alzheimer’s disease, as well as protecting neurons from oxidative and neural damage, two phenomena which occur at the origin of many diseases affecting the central nervous system.

In this study researchers have used different biochemical and molecular analysis techniques, with the help of specific antibodies, to detect different neuronal markers implied in the process of differentiation.

The group of researchers led by Dr Unzeta has spent years studying the effects oxidases have on oxidative stress as a factor implied in neurodegenerative disorders such as Parkinson and Alzheimer’s disease, and the effects of different natural products with anti-inflammatory and antioxidant properties in different experimental models of Alzheimer’s disease.

The study forms part of the CENIT project, which was awarded to La Morella Nuts in 2006 under the auspices of the INGENIO 2010 programme, with the objective of establishing methodologies for the design, evaluation and verification of functional foods which may protect against cardiovascular diseases and Alzheimer’s disease. With 21.15m euros in funding and a duration of four years, the project has included the participation of 50 doctors and technicians from nine different companies, four universities (7 departments) and 2 research centres.

Reference article: “A diet enriched in polyphenols and polyunsaturated fatty acids, LMN diet, induces neurogenesis in the subventricular zone and hippocampus of adults mouse brain”. Valente et al., 2009, Journal of Alzheimer’s Disease, Volume 18:4. Valente T., Hidalgo, J., Bolea, I., Ramrez B., Angls, N., Reguant, J., Morell, J.R., Gutirrez, C., Boada, M., Unzeta, M.

Source: Maria Jesus Delgado

Universitat Autonoma de Barcelona

The Birth Of New Neurons Boosted By Polyphenols And Polyunsaturated Fatty Acids

Originally from:
http://www.medicalnewstoday.com/articles/172157.php

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Univ. Of Nebraska Board Of Regents Votes To Maintain Current Embryonic Stem Cell Policy

November 25, 2009 By: Category: Uncategorized Comments

The University of Nebraska Board of Regents last week voted 4-4 not to restrict embryonic stem cell research policy beyond current federal and state limits, the New York Times reports. According to the Times, the tie vote defeats a “rare effort” at a university system to curtail stem cell research beyond state and federal law. The decision leaves the school’s policy in line with President Obama’s guidelines expanding limits on federal funding that can go toward the research.
Groups that oppose embryonic stem cell research considered the vote a new front to fuel national debate on the matter, according to the Times. Supporters and university administrators said the decision will allow the university to continue attracting top researchers and apply for federal grants in the field.

Reprinted with kind permission from http://www.nationalpartnership.org. You can view the entire Daily Women’s Health Policy Report, search the archives, or sign up for email delivery here. The Daily Women’s Health Policy Report is a free service of the National Partnership for Women & Families, published by The Advisory Board Company.

2009 The Advisory Board Company. All rights reserved.

Univ. Of Nebraska Board Of Regents Votes To Maintain Current Embryonic Stem Cell Policy

Originally from:
http://www.medicalnewstoday.com/articles/172120.php

Cord Blood Success Story

November 24, 2009 By: admin Category: Cord Blood Videos Comments

Stem Cell Transplant Improves Cerebral Palsy Symptoms Baby John was suffering from symptoms caused by a pediatric stroke. John received an umbilical stem cell transplant, from the cord blood that his parents banked when he was born. The cord blood transfusion proved to be a success and Baby John has since shown major signs of improvement. For more information see: www.mazecordblood.com

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Is Cord Blood Banking Right For You?

November 21, 2009 By: admin Category: Diseases Treament Comments

Saving your baby’s umbilical cord blood allows it to be cryogenically stored, and then available if your child later becomes sick and needs a bone marrow transplant. Umbilical cord blood was discarded until the 1970’s, when researchers discovered that umbilical cord blood could save lives under certain circumstances. How do you decide on cord blood banking? Many soon-to-be parents ask this very question. Here are some things to consider when deciding on whether or not to bank your baby’s umbilical cord blood.

This type of transplant would be ‘autologous’ and is different than the more common ‘allogenic’ transplants that might be done from a sibling or other relative or an unrelated donor. Our own blood is the best choice for a transplant.

Often times, cord blood banking can save a baby’s life. But still, there are many other factors to consider. Price seems to be the number one roadblock, with the complete cost being around $3,000. So, you should certainly not feel guilty if you cannot bank your child’s cord blood. Should you even consider cord blood banking? That part will be up to you.

However, if you already have a child or family member that has a condition that can be treated with a stem cell transplant (such as sickle cell anemia, thalassemia, aplastic anemia, leukemia, metabolic storage disorders and certain genetic immunodeficiencies), then you defenitely should consider banking your child’s umbilical cord blood. However, the average baby without risk factors has a very low chance of ever needing his or her cord blood.

On the other hand, some doctors and researchers support saving umbilical cord blood as a source of blood-forming stem cells in every delivery. This is mainly because of the promise that stem-cell research holds for the future. The majority of people would have little use for stem cells now, but research into the use of stem cells for treatment of disease is ongoing – and the future looks promising.

You may also want to donate your baby’s cord blood. This is possible through non-profit cord blood banks that use it for research or to save the life of another child.

Overall, cord blood banking looks to have a promising future. It’s defenitely an option you should look into. After you’ve studied the facts and your family history, you should be able to make a much more informed decision on what’s right for you.

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Beyond Genomics, Biologists And Engineers Decode The Next Frontier

November 21, 2009 By: Category: Stem Cells Comments

A team of Princeton biologists and engineers has dramatically improved the speed and accuracy of measuring an enigmatic set of proteins that influences almost every aspect of how cells and tissues function. The new method offers a long-sought tool for studying stem cells, cancer and other problems of fundamental importance to biology and medicine.

The research allows scientists an unprecedented look at a special class of proteins called histones, which are at the core of every chromosome and control the way instructions in DNA are carried out. Despite rapid progress in understanding the information encoded in DNA and genes, scientists have achieved much less insight into the so-called “histone code,” which determines why a gene in one cell functions differently than the same gene in another cell.

“We take a cutting-edge approach to a field that has been using more or less the same techniques for the past 15 years,” said Benjamin Garcia, assistant professor of molecular biology, who supervised the experimental aspects of the study.

The technique reduces by a factor of 100 the time it takes to analyze histones, while requiring far less sample material and achieving much more nuanced results than existing methods, said Christodoulos Floudas, the Stephen C. Macaleer ‘63 Professor in Engineering and Applied Science, who oversaw computational aspects of the research.

The researchers published their results in the October issue of Molecular & Cellular Proteomics. Their paper was selected as a “must-read” article in Faculty of 1000 Biology, an online journal that selects the most interesting papers in all biology based on peer opinions. A second paper detailing the computational part of the research appeared in Molecular & Cellular Proteomics this month.

Collaborators on the papers also include postdoctoral researcher Nicolas Young and graduate student Mariana Plazas-Mayorca of Garcia’s group and graduate students Peter DiMaggio and Richard Baliban of Floudas’ group in chemical engineering.

Despite carrying identical DNA, all cells in a body aren’t identical — a cell in the kidney looks and functions very differently from one in the brain. What makes this specialization possible is a set of instructions stored outside of genes or DNA — “epigenetic” information — that helps each cell adapt to its context. Key players in this process are histones, tiny protein spindles that the 6-foot-long DNA molecule wraps itself around in forming a chromosome.

Scientists have long known that histones acquire a variety of small chemical decorations — small molecules attached here and there along the length of the histone. The type and location of these add-ons can regulate nearby genes. Single modifications are known to turn genes on or off, but what happens when multiple modifications occur in combinations — the “histone code” — remains a mystery.

“The ability to understand this phenomenon and control it with great precision would be revolutionary to medicine,” said Young.

Distinguishing between various modified forms of a histone has been challenging because several combinations of different modifications can have nearly the same mass. Indeed, under conventional tests two histones with very different functions could appear identical if they have the same set of modifications but at different locations on the molecule. Before now, efforts to distinguish such subtle differences were extremely difficult and time consuming. “We have now developed the first practical means to do this,” said Young.

The Princeton team combined physical, chemical and mathematical techniques for separating one histone variation from another. First they passed a mix of various histones through a very thin, long tube containing a specially designed material that causes different histone forms to emerge from the tube at different times over a two- to three-hour period. They then bombarded selected molecules with ions to break them apart and send a flood of data into a computer program for high-throughput analysis.

“We may get several thousand sets of such measurements over the course of a single experiment,” said DiMaggio.

When seemingly similar histones are broken into small fragments, differences in the locations of modifications become more apparent. The computer algorithm — based on an area of math called integer linear optimization — repeatedly compares all the fragments until it produces a highly accurate list of modifications and their locations.

“To see separation of nearly identical species and identify and quantify them with high confidence is very exciting,” said Young. He also noted that of the many millions of combinations of modifications possible only a few hundred actually appear in real human cells. This observation implies that combinations of these relatively few modifications form a code that can now be deciphered.

The next step will be to link specific patterns of modifications with observable changes in cells. For example, when normal cells transform themselves into cancerous cells, scientists could track the corresponding changes in the histones. Similarly, scientists could identify particular histone codes that are required for stem cells to change into specific tissue types, such as nerve cells or insulin-producing cells. Understanding and potentially reprogramming these processes could have important implications for regenerative medicine, cancer and other diseases.

As a start, the researchers are collaborating with biologists from the University of California- Los Angeles to identify histone codes relevant for stem cell behavior. “We’ve shown we can measure modified histone forms, but there’s so much to do now,” said Garcia. “This is really the beginning of some true biological breakthroughs.”

The work was supported by the American Society for Mass Spectrometry, the National Science Foundation, the National Institutes of Health and the Environmental Protection Agency. The National Science Foundation recently awarded a grant of $1.3 million to Floudas, Garcia and Joshua Rabinowitz, associate professor in the Department of Chemistry and the Lewis-Sigler Institute for Integrative Genomics, to develop the techniques into a generalized platform for the analysis of proteins and other biomolecules.

Source: Steven Schultz

Princeton University, Engineering School

Beyond Genomics, Biologists And Engineers Decode The Next Frontier

Originally from:
http://www.medicalnewstoday.com/articles/171674.php

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Advanced Cell Technology Files IND With FDA For First Human Clinical Trial Using Embryonic Stem Cells To Treat Eye Disease

November 20, 2009 By: Category: Stem Cells Comments

Advanced Cell Technology, Inc. (OTCBB:ACTC) announced that it filed an Investigational New Drug (IND) Application with the US Food and Drug Administration (FDA) to initiate a Phase I/II multicenter study using embryonic stem cell derived retinal cells to treat patients with Stargardt’s Macular Dystrophy (SMD). Among the most common causes of untreatable blindness in the world are degenerative diseases of the retina. As many as 10 million people in the United States have photoreceptor degenerative disease. While most of these patients have Age-Related Macular Degeneration (AMD), a smaller number of patients have Stargardt’s, an Orphan disease and one of the most common forms of juvenile macular blindness. The treatment for eye disease uses stem cells to re-create a type of cell in the retina that supports the photoreceptors needed for vision. These cells, called retinal pigment epithelium (RPE), are often the first to die off in SMD and AMD, which in turn leads to loss of vision.

While there is currently no treatment for SMD, several years ago ACT and its collaborators found that human embryonic stem cells could be a source of RPE cells. Subsequent studies found that the cells could restore vision in animal models of macular degeneration. In the Royal College of Surgeon (RCS) rat model, implantation of RPE cells resulted in 100% improvement in visual performance over untreated controls without any adverse effects. The cells survived for more than 220 days and sustained extensive photoreceptor rescue. Functional rescue was also achieved in the ‘Stargardt’s’ mouse with near-normal functional measurements recorded at more than 70 days.

“It has been over a decade since human embryonic stem cells were first discovered,” said Dr. Robert Lanza, ACT’s Chief Scientific Officer. “The field desperately needs a big clinical success. After years of research and political debate, we’re finally on the verge of showing the potential clinical value of embryonic stem cell research. Our research clearly shows that stem cell-derived retinal cells can rescue visual function in animals that otherwise would have gone blind. We are hopeful that the cells will be similarly efficacious in patients.”

The Phase I/II trial will be a prospective, open-label study that is designed to determine the safety and tolerability of the RPE cells following sub-retinal transplantation to advanced patients with SMD. A total of twelve patients will be enrolled into the study at three clinical sites, including the Casey Eye Institute in Portland, Oregon (headed by Dr. Peter Francis of the Oregon Health & Sciences University); the University of Massachusetts Memorial Medical Center, Worcester, Massachusetts (headed by Dr. Shalesh Kaushal, Chair of the Department of Ophthalmology); and the UMDNJ – New Jersey Medical School, Newark, New Jersey (headed by Dr. Marco Zarbin, Chair, Institute of Ophthalmology and Visual Science). “It is an honor for us to be working with ophthalmology researchers of such high caliber,” said Edmund V. Mickunas, Advanced Cell’s Vice President of Regulatory Affairs. “They have been instrumental as collaborators on the clinical trial design and their input has been invaluable.”

“The filing of this IND places Advanced Cell Technology in position to help lead the industry in validating the stem cell platform,” said William M. Caldwell IV, Advanced Cell’s Chairman and CEO. “Over the past year, we have taken important steps to advance our RPE program while overcoming significant financial challenges. Advanced Cell today is uniquely positioned within the regenerative medicine industry; as it has the technology, a renown scientific and development team and access to capital to become one of the first companies to make the use of an embryonic stem cell derived therapy a reality in treating a major unmet medical need.”

Source
Advanced Cell Technology, Inc.

Advanced Cell Technology Files IND With FDA For First Human Clinical Trial Using Embryonic Stem Cells To Treat Eye Disease

Originally from:
http://www.medicalnewstoday.com/articles/171719.php

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Burns Patients Awaiting Skin Grafts: Human Embryonic Stem-Cells Could Be Used To Generate Temporary Skin

November 20, 2009 By: Category: Stem Cells Comments

A study in this week’s edition of The Lancet reports that the use of human embryonic stem-cells (hESCs) is a promising alternative for producing temporary skin substitutes for patients awaiting skin grafts after, for example, serious burn injuries. The article is the work of Dr Christine Baldeschi, INSERM and Institute for Stem Cell Therapy and Exploration of Monogenic Diseases, Evry Cedex, France, and colleagues.

For more than two decades, patients with serious burns have benefited from cell therapy to help them recover from their injuries. In this therapy, the patient’s own skin cells (keratinocytes) are taken. Then more are grown in the laboratory and used to replace the damaged skin. But the major disadvantage is that there is a three week period needed to grow enough cells. This puts the patients at risk of dehydration and infection. Decellularised skin from deceased persons can be used to cover wounds during this period. However, availability is limited and the tissue is often rejected by the host. To overcome the problem of accessibility, there has been active search and development for inert synthetic and biosynthetic matrices. Presently however, these substitutes have not replaced skin from deceased persons in large burns since they increase the risks of rapid graft rejection and disease transmission. This is due to the fact that they contain bovine collagen and adult allogenic skin cells.

In this research, the hESC were seeded on feeder cells using a pharmacological treatment over forty days. This treatment drives hESCs towards becoming keratinocytes linage. This is done by following biological steps that lead to epidermis formation during embryonic development. The team were capable to generate a population of cells that presented the characteristics of keratinocytes. Once placed on an artificial matrix, the cells were able to form a layer of skin. Just twelve weeks after grafting onto five mice, the skin layer derived from the hESCs had a structure similar to human skin.

The authors explain: “We have shown that keratinocytes can be derived from hESCs… Growing human epidermis from hESCs could have clinical relevance as an unlimited resource for temporary skin replacement in patients with large burns awaiting autologous grafts.”

They include that future research should assess whether or not this technology could extend the time needed to grow enough cells for a permanent graft, or if keratinocyte hESCs could be used for a permanent graft in cases where a permanent graft using the patients’ own keratinocytes is not possible.

In an associated comment, Dr Holger Schlter and Dr Pritinder Kaur, Epithelial Stem Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia, remark: “This report takes research into regenerative skin stem cells to the next level…This finding suggests that keratinocyte allografts derived from hESC keratinocytes could be transplanted onto burnt patients awaiting skin grafts with a reduced risk of rejection.”

“Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study”
Hind Guenou, Xavier Nissan, Fernando Larcher, Jessica Feteira, Gilles Lemaitre, Manoubia Saidani, Marcela Del Rio, Christine C Barrault,
Franois-Xavier Bernard, Marc Peschanski, Christine Baldeschi, Gilles Waksman
Lancet 2009; 374: 1745-53
The Lancet

Written by Stephanie Brunner (B.A.)

Copyright: Medical News Today

Not to be reproduced without permission of Medical News Today

Burns Patients Awaiting Skin Grafts: Human Embryonic Stem-Cells Could Be Used To Generate Temporary Skin

Originally from:
http://www.medicalnewstoday.com/articles/171582.php

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